Postupak s novorođenčetom majke kolonizirane Streptococcus agalactiae (GBS)
DOI:
https://doi.org/10.13112/pc.1244Ključne riječi:
Dojenče, Novorođenče; Sepsa; Streptococcus agalactiaeSažetak
Novorođenačka sepsa ostaje jedan od vodećih uzroka morbiditeta i mortaliteta u neonatalnoj dobi, unatoč značajnom napretku u perinatalnoj skrbi. Streptococcus agalactiae (GBS) i dalje je najčešći uzročnik rane novorođenačke sepse (engl. early-onset sepsis, EOS). Pravodobna identifikacija trudnica koloniziranih GBS-om i adekvatna intrapartalna antibiotska profilaksa (IAP)
ključne su mjere u prevenciji EOS-a. Ovaj članak prikazuje epidemiologiju, čimbenike rizika, preventivne strategije te suvremene pristupe procjeni rizika i zbrinjavanju novorođenčadi majki koloniziranih GBS-om.
Reference
1. Shane AL, Sánchez PJ, Stoll BJ. Neonatal sepsis. Lancet.
2017;390:1770-80. doi: 10.1016/S0140-6736(17)31002-4.
2. Stoll BJ, Puopolo KM, Hansen NI, Sánchez PJ, Bell EF, Carlo
WA, et al. Early-onset neonatal sepsis 2015 to 2017, the
rise of Escherichia coli, and the need for novel prevention
strategies. JAMA Pediatr. 2020;174:e200593. doi: 10.1001
/jamapediatrics.2020.0593.
3. Puopolo KM, Lynfield R, Cummings JJ; Committee on Fetus
and Newborn; Committee on Infectious Diseases. Management of infants at risk for group B streptococcal disease. Pediatrics. 2019;144:e20191881. doi: 10.1542/peds.
2019-1881.
4. Verani JR, McGee L, Schrag SJ; Division of Bacterial Diseases, National Center for Immunization and Respiratory
Diseases, Centers for Disease Control and Prevention.
Prevention of perinatal group B streptococcal disease: revised guidelines from CDC, 2010. MMWR Recomm Rep.
2010;59:1-36.
5. Schrag SJ, Zywicki S, Farley MM, Reingold AL, Harrison LH,
Lefkowitz LB, et al. Group B streptococcal disease in the
era of intrapartum antibiotic prophylaxis. N Engl J Med.
2000;342:15-20. doi: 10.1056/NEJM200001063420103.
6. Weston EJ, Pondo T, Lewis MM, Martell-Cleary P, Morin C,
Jewell B, et al. The burden of invasive early-onset neonatal
sepsis in the United States, 2005-2008. Pediatr Infect Dis.
J 2011;30:937-41. doi: 10.1097/INF.0b013e318223bad2.
7. Escobar GJ, Puopolo KM, Wi S, Turk BJ, Kuzniewicz MW,
Walsh EM, et al. Stratification of risk of early-onset sepsis
in newborns ≥34 weeks’ gestation. Pediatrics. 2014;133:
30-6. doi:10.1542/peds.2013-1689.
8. Kuzniewicz MW, Puopolo KM, Fischer A, Walsh EM, Li S,
Newman TB, et al. A quantitative, risk-based approach to
the management of neonatal early-onset sepsis. JAMA
Pediatr. 2017;171:365-71. doi: 10.1001/jamapediatrics.
2016.4678.
9. Kaiser Permanente Neonatal Early-Onset Sepsis Calculator [Internet]. Oakland (CA): Kaiser Permanente; [cited
2026 Mar 9]. Available from: https://neonatalsepsiscalculator.kaiserpermanente.org
10. Benitz WE. Adjunct laboratory tests in the diagnosis of
early-onset neonatal sepsis. Clin Perinatol. 2010;37:42138. doi: 10.1016/j.clp.2010.02.004.
11. Polin RA; Committee on Fetus and Newborn. Management of neonates with suspected or proven early-onset
bacterial sepsis. Pediatrics. 2012;129:1006-15. doi: 10.
1542/peds.2012-0541.
12. Cotten CM. Adverse consequences of neonatal antibiotic
exposure. Curr Opin Pediatr. 2016;28:141-9. doi: 10.1097/
MOP.0000000000000338.
Preuzimanja
Objavljeno
Broj časopisa
Rubrika
Licenca
Autorska prava (c) 2026 Branimir Peter, Jelena Mažibrada Spasojević
Ovo djelo je licencirano pod licencom Creative Commons Attribution 4.0 Međunarodna licenca.
By publishing in Paediatria Croatica, authors retain the copyright to their work and grant others the right to use, reproduce, and share their research articles in accordance with the Creative Commons Attribution License (CC BY 4.0), which allows others to distribute and build upon the work as long as they credit the author for the original creation.
